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VITAMIN D3
Background
"Vitamin D receptors (VDRs) are located predominantly in the nucleus of cells, where they act as transcription factors regulating the expression/transcription of genes (genomic pathways) that control cell-specific biological functions. Furthermore, a small proportion of the VDRs are found in the cytosol, (the aqueous component of the cytoplasm of a cell, within which various organelles and particles are suspended) where they modulate various enzymes and signaling pathways (non-genomic pathways).
Bottom line, vitamin D is essential for all our body tissues! A healthy vitamin D blood level is 40-50 ng/mL.
Vitamin D Daily Intake
There are many "versions" to the proper daily intake of vitamin D supplement. We recommend to follow the recommendations of Dr. Berg "I started taking 5,000 IUs of vitamin D in May 2020 and started feeling good and I increased it to 10,000 IUs and started feeling great".
According to Dr. Gundry - another prominent health figure that we follow, the minimum daily intake should be 5,000 IUs (min. 6:31) .
It is recommended that taking vitamin D supplement capsules should be complemented with some fat be it in the capsules or with fat (e.g. avocado) that you have in your meal.
Vitamin D Deficiency Implications
"Over the past decades, scientists gathered overwhelming evidence indicating that the observed global vitamin D deficiency not only has a negative impact on human skeletal system, but also facilitates development and progression of multiple disease of civilization, including cardiovascular diseases, diabetes, autoimmune disease, and cancer.""The active form of vitamin D (1,25(OH)2D3, calcitriol) regulates calcium–phosphate homeostasis through the interaction with vitamin D receptor (VDR). It also has a huge impact on the proper functioning of musculoskeletal, immune, nervous, and cardiovascular systems".
Backgroud
Vitamn D Daily Intake
Vitamin D Deficiency Implications
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